a decreasing trendp -value = 0.0023
As showed in Figure 3 , all the Amsel criteria showed a decreasing trend in Active group at T1 sampling time compared to T0 (Clue cell presence p -value = 0.0023; Homogenous vaginal discharge p -value = 3.05 × 10 −5 ; Positive amine test p -value = 0.0018; Vaginal pH > 4.5 p -value = 0.049).