Barely Significant
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The updated development of blood-based biomarkers for Huntington's disease.

J Neurol · 2023 · PMC9873222 · PMID 36692635

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an increasing trendno p-value reported
HD has an incidence of 10.6–13.7 per 100,000 individuals in western populations and has shown an increasing trend in the past two decades [ 2 , 4 , 5 ].

also in 63,971 other papers

a decreasing trendno p-value reported
observed a significant difference among low, medium and high gene-expanded groups, showing a decreasing trend [ 160 ].

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.