Pigs with an <i>INS</i> point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN.

Differences with a probability value ( p ) ≥ .05 were considered statistically significant, and those with a probability value ≥.1 were considered marginally significant. 2.11 Study approval The Institutional Animal Care and Use Committee of Tokushima University approved the animal experiments conducted in the present study (approval number: T2019-11). 3 Results 3.1 Experiment 1: Effect of Scr7 concentration on point mutation introduction efficiency The concentration of Scr7 did not have a statistically significant effect on blastocyst formation rates from electroporated zygotes ( Figure 2A ).

also in 26,082 other papers