Sex differences in drug effects and/or toxicity in oncology.

Curr Res Pharmacol Drug Discov · 2023 · PMC9881040 · PMID 36714036

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might be significantno p-value reported

Since the pharmacokinetics of 5-FU is more accurately predicted by fat-free mass in addition to total body weight than traditional anthropometric measurements, gender variations in the composition of the body, especially the significantly more significant percentage of metabolically active, fat-free body mass in males ( Wagner et al., 2019 ), might be significant too ( Gusella et al., 2002 ).

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