USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression.

Cell Death Dis · 2023 · PMC9883245 · PMID 36707504

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a decreasing trendno p-value reported

In this process, the expression of E3 ligase TRIM26, which is proved to restrain HCC in our previous research, shows a decreasing trend.

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