Autologous stem cell transplantation (ASCT) for acute myeloid leukemia in patients in first complete remission after one versus two induction courses: A study from the ALWP of the EBMT.

Interestingly, in the historical era of ACT with marrow purged in vitro by mafosfamide, the efficacy of purging demonstrated by a reduction in relapse incidence post‐transplant was highly significant in slow and not rapid remitters. 15 We thus performed a study to answer this question for the ACT and analyzed whether the results of ACT in AML patients transplanted while in the first remission would be better in those achieving CR1 after one induction in comparison to those achieving it only after a second chemotherapy course using the European transplant registry. 2.

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