Genetic association and causal inference between lung function and venous thromboembolism.

Respir Res · 2023 · PMC9885683 · PMID 36717884

Europe PMC DOI

hedged sentences

0.0200

closest p · 0.4× alpha

0.0500

boldest claim

The sentences

suggestive of significanceP = 0.020actually significant

The weighted median estimate was suggestive of significance (OR 0.785, 95% CI 0.639–0.963, P = 0.020), which highlights the necessity for MVMR analysis.

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borderline significantP = 0.050actually significant

Notably, the direct causal effect of PE on FEV1 was borderline significant (OR 0.921, 95% CI 0.848–1.000, P = 0.050), which was inconsistent with UVMR and should be interpreted with caution (Table 3 ).

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