a trend toward significancep = 0.07
Sham rats showed a trend toward significance in decreased time in the open arms from 7 days to 1 month (63.26 ± 29.10 vs. 24.13 ± 26.03; p = 0.07), with a gradual increase in the open arms over the rest of the testing period, such that more time was spent in the open arms at 12 months compared to 1 month (24.13 ± 26.03 vs. 66.40 ± 40.46; p < 0.05).