Low copy numbers of complement <i>C4</i> and <i>C4A</i> deficiency are risk factors for myositis, its subgroups and autoantibodies.

Ann Rheum Dis · 2023 · PMC9887400 · PMID 36171069

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highly significantno p-value reported

Our data consistently showed that low copy numbers of C4T and C4L , and C4A deficiency are highly significant risk factors for IIM and its major subgroups, with medium to large effect sizes 45 or ORs between 1.7 and 3.7.

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