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Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids.

J Cell Mol Med · 2023 · PMC9889627 · PMID 36644817

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Similarly, putative ON centre‐like responses of RGCs were found in both conditions, revealing a firing rate increase after WLP and showing a statistical trend in % firing rate change in the presence of iMG, with a slight increase in the number of responding RGCs in the retinal organoids with iMG (10.5% in RO + iMG and 7.5% in RO) (Figure 4A , p = 0.065).

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