Mediation roles of neutrophils and high-density lipoprotein (HDL) on the relationship between HLA-DQB1 and rosacea.

Ann Med · 2022 · PMC9891224 · PMID 35622385

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on the brink of significanceno p-value reported

Besides, HLA-DQB1 03:03/03:03 (3.0% in cases, and 0.5% in controls; OR = 12.00, 95%CI: 1.12 ∼ 128.84, p = 0.040) genotypes were positively associated with risk of rosacea, and HLA-DQB1 03:03/05:02 (3.5% in cases, and 1.5% in controls; OR = 4.67, 95%CI: 0.83 ∼ 26.24, p = 0.080) was found on the brink of significance correlated with rosacea ( Supplementary Table 2 ).

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marginal significanceno p-value reported

Contrarily, HLA-DQB1*03:03 (10.8% in rosacea, and 8.5% in controls; OR = 1.84, CI: 0.97 ∼ 3.49, p = 0.063) and HLA-DQB1*06:02 (3.5% in rosacea, and 2.3% in controls; OR = 2.26, CI: 0.87 ∼ 5.86, p = 0.094) alleles were positively associated with rosacea with marginal significance ( Supplementary Table 1 ).

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