A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes.

Cancer Res · 2023 · PMC9896023 · PMID 36449018

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highly significantP < 0.0001actually significant

We detected a highly significant ( P < 0.0001) increase in NRas-positive hepatocytes in liver tissue of WT mice injected with oncogenic NRas 44 days post PH compared with the control (∼18% vs. less than 10%, Fig. 1E ).

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