The Interaction between Four Polymorphisms and Haplotype of <i>ABCB1</i>, the Risk of Non-Small Cell Lung Cancer, and the Disease Phenotype.

The two groups also demonstrated a highly significant difference in common haplotype frequency ( p =0.01).

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Although the investigated polymorphisms were not related to demographic features, clinicopathological lung tumour characteristics, or blood morphology indices, marginally significant correlations were found with some variables: C1236T with age of disease onset ( p =0.0410); C3435T with smoking status ( p =0.0561).

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Comparisons of the frequencies of the C3435T genotypes between patients stratified according to smoking status were of only borderline significance (Supplement Table A4 ). 4.3.

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