Osteocalcin ameliorates cognitive dysfunctions in a mouse model of Alzheimer's Disease by reducing amyloid β burden and upregulating glycolysis in neuroglia.

Cell Death Discov · 2023 · PMC9902399 · PMID 36746932

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0700

boldest claim

The sentences

an increasing trendP > 0.05actually significant

In addition, although there was no significant difference, there was an increasing trend in the crossings of the previous platform after OCN treatment in AD mice ( P > 0.05, Fig. 1D ).

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marginal significanceP = 0.070so close (0.05 < p ≤ 0.1)

OCN upregulated Pdk1 at both mRNA and protein levels while upregulated Ldha protein level of a marginal significance ( P = 0.070) (Fig. 5E–G ).

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