an obvious trendP = 0.13
Bui et al ( 29 ) demonstrated survival improvement in patients diagnosed in the recent era compared to old era (The 1-year survival rate: 13.3% (1975–1998), 40.9% (1999–2004), 50% (2005–2010), and 59.7% (2011–2016), p -value = 0.0064), however, Yin et al ( 30 ) study did not show this survival advantages although there was an obvious trend ( P = 0.13).