Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2.

Proc Natl Acad Sci U S A · 2022 · PMC9907126 · PMID 36534812

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0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

a decreasing trendP = 0.081so close (0.05 < p ≤ 0.1)

The result showed that after tumor initiation, instead of tumor promotion, gut commensal bacteria depletion in mice induced a slight decrease in tumor number ( P = 0.043) and a decreasing trend of the LW/BW ratio ( P = 0.081) and SW/BW ratio ( P = 0.100) ( Fig. 2 B and C ).

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