Discussion Accurately quantifying podocyte number is extremely significant in assisting the diagnosis of kidney diseases and guiding clinical medication especially in diabetic kidney disease, focal segmental glomerulosclerosis (FSGS), and other podocyte injury diseases with nephrotic syndrome or nephrotic range proteinuria as the main manifestation, because of the pivotal role of podocytes in maintaining glomerular filtration barrier's structure and preventing the occurrence of proteinuria [ 15 , 16 , 39 – 43 ].
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Quantifying Podocyte Number in a Small Sample Size of Glomeruli with CUBIC to Evaluate Podocyte Depletion of db/db Mice.
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