DSS-induced colitis activates the kynurenine pathway in serum and brain by affecting IDO-1 and gut microbiota.

Front Immunol · 2022 · PMC9908955 · PMID 36776388

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did not achieve significanceno p-value reported

The protein level of IDO-1 in liver did not achieve significance between the two groups ( Figures 3A, D ), while a significant increase (5.9 times) of IDO-1 mRNA level was observed in 2% DSS group compared with Control group ( Figure 3G ).

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