Comparing Transgenic Production to Supplementation of ω-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders.

During the ipITT, the improvement of glucose response failed to reach significance in both Fat-1 groups compared with their WT littermates (genetic effect, P = .11) ( Figure 2A ).

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In stark contrast, exogenous ω-3 PUFA administration through dietary exposure clearly impacts microbiota function, as revealed by the highly significant decreased fecal levels of LPS and flagellin ( Figure 3H – I ).

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