failed to achieve significancep = 0.0421
Despite this, the recently published final results of the ORACLE phase III study comparing oral 5-azacytidine to investigator’s choice in R/R AITL failed to achieve significance in the primary endpoint of PFS with a median PFS in the 5-azacytidine group of 5.6 months versus 2.8 months in the standard arm (p = 0.0421) ( 140 ).