Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue.

Cells · 2023 · PMC9913959 · PMID 36766757

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a decreasing trendno p-value reported

The overall quantification revealed a decreasing trend with respect to all four cell populations (DDX4+/Ki-67+, PIWIL4+/KI-67+, DDX4+/Ki-67-, PIWIL4+/Ki-67-) starting from the native tissue up to cultivation week 3 with partly significant and partly non-significant statistical values ( Figure 5 a,b).

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highly significantno p-value reported

Younger children, in contrast, displayed highly significant, larger mitochondria (MT), indicating a different mechanism of energy production.

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