Three genes responded to the mix of low-level cytokines, with PDGFC and ACAN reduced in their amount and CXCL9 being strongly upregulated, with the ratio with high IL1β (7.4) that almost reached significance ( p -value of 0.0517).
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Inflammatory Treatment Used to Mimic Osteoarthritis and Patients' Synovial Fluid Have Divergent Molecular Impact on Chondrocytes In Vitro.
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