The impact of RAS mutation on the treatment strategy of colorectal cancer.

Med Pharm Rep · 2023 · PMC9924809 · PMID 36818322

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Post hoc analysis of data collected prospectively from PETACC-8 demonstrated the detrimental role KRAS mutation has on colon cancer outcome, being associated with a statistically significant increased risk of relapse and shorter DFS for codon 12 mutations and a borderline significance for codon 13 mutations [ 40 , 41 ].

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