Nanocell COVID-19 vaccine triggers a novel immune response pathway producing high-affinity antibodies which neutralize all variants of concern.

Front Immunol · 2022 · PMC9929940 · PMID 36818474

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highly significantno p-value reported

A highly significant increase in IL-21 was observed only in EDV-COVID-αGC treated mice ( Figure 1L ) demonstrating the addition of αGC was essential in activating CD4 + T FH cells likely due to iNKT-licensed DC activation of T FH cells as described above.

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