Therapeutic role of ursodeoxycholic acid in colitis-associated cancer via gut microbiota modulation.

Mol Ther · 2023 · PMC9931610 · PMID 38556635

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highly significantno p-value reported

Highly significant upregulation of BA receptors, such as farnesoid X receptor ( Fxr ) and pregnane X receptor ( Pxr ), was observed in the intestine of UDCA-treated mice, whereas these receptors were significantly downregulated after treatment with the antibiotic cocktail ( Figures S4 A and S4B).

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