AAV- based vector improvements unrelated to capsid protein modification.

Front Med (Lausanne) · 2023 · PMC9935841 · PMID 36817775

Europe PMC DOI

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might be significantno p-value reported

The latest studies have revealed the ITRs to be insufficient compared with the Rep proteins in binding to cellular sites of DNA damage that might be significant in AAV2 genome integration ( 31 ).

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