highly significantp -value = 4.3 × 10 − 102
This highly significant overlap ( p -value = 4.3 × 10 − 102 by hypergeometric test, 2.4-fold-enriched) demonstrates that alteration of regulatory complex binding is strongly predictive of a change in gene expression (i.e., 70%; 359 / 510) and suggests possible mechanisms for the observed gene expression effects.