Comparison of ultrasensitive and mass spectrometry quantification of blood-based amyloid biomarkers for Alzheimer's disease diagnosis in a memory clinic cohort.

Alzheimers Res Ther · 2023 · PMC9938625 · PMID 36800984

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0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a statistical trendp = 0.06so close (0.05 < p ≤ 0.1)

Simoa Aβ 42/40 was a significant predictor of Aβ + status in a univariate model but the effect soothes to a statistical trend in a multivariate model ( p = 0.06); this was not the case for the IPMS-Shim biomarkers which were both significant predictors in each type of model.

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