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The Role of IL-6 and TMEM100 in Lumbar Discogenic Pain and the Mechanism of the Glycine-Serine-Threonine Metabolic Axis: A Metabolomic and Molecular Biology Study.

J Pain Res · 2023 · PMC9939909 · PMID 36815126

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a decreasing trendP < 0.05actually significant
With the degeneration of intervertebral discs aggravating, the peak fragmentation increased and the integral value decreased (P < 0.05); Besides, Creatine (Cr) is an important energy storage substance that determines the flow direction and distribution of ATP, exhibiting a decreasing trend with the exacerbation of intervertebral disc degeneration (P < 0.05).

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