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Pyruvate Kinase 2, an Energy Metabolism Related Enzyme, May Have a Neuroprotective Function in Retinal Degeneration.

ASN Neuro · 2023 · PMC9940218 · PMID 36799552

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By contrast, we could not observe any significant differences in photoreceptor death in the explants with PKM2 activation from the rd2 model compared to their untreated counterparts ( Figure 2A –B, E), although a reduction that came close to being statistically significant was observed.

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