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Global historical retrospect and future prospects on biomarkers of heart failure: A bibliometric analysis and science mapping.

Heliyon · 2023 · PMC9942007 · PMID 36825183

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a decreasing trendno p-value reported
Although the total number of themes continued to increase over the four periods, the overlapping of themes increased further and the innovation index showed a decreasing trend.

also in 47,180 other papers

an increasing trendno p-value reported
Studies on HF biomarkers began to trickle in around the 1990s, with no more than 10 documents published between 1989 and 1996 yet an increasing trend.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.