Multidrug-Loaded Lipid Nanoemulsions for the Combinatorial Treatment of Cerebral Cavernous Malformation Disease.

Indeed, although we observed a positive trend and a good efficacy of the combined pharmacological approach in this preliminary in vitro study, additional molecular biomarkers unbiasedly identified through genome-wide omics studies [ 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 ] should be analyzed in future in vitro and in vivo studies in order to validate this innovative combined therapeutic approach.

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