CXCR2 Antagonist RIST4721 Acts as a Potent Chemotaxis Inhibitor of Mature Neutrophils Derived from Ex Vivo-Cultured Mouse Bone Marrow.

Next, we tested a wide range of KC concentrations (10–250 ng/mL) and also observed an increasing trend in chemotaxis levels, but concentrations higher than 100 ng/mL showed little change, and therefore this dose was considered optimal ( Figure 2 b).

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