Progressive Ataxia, Memory Impairments, and Seizure Episodes in <i>Spna2 R1098Q</i> Mouse Variant Affecting Alpha II Spectrin's Scaffold Stability.

However, consistently with rotarod results, in the case of young, 8-wk-old mice, the difference in the mean numbers of foot slips between the R1098Q (0.01250 ± 0.003070 errors/cm) and WT (00956 ± 0.00233 errors/cm) was barely significant ( p = 0.0491) ( Figure 1 B).

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We could find a highly significant difference between the performance of 8-wk-old R1098Q mice in comparison to their WT littermates.

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