Stationary Trend in Elevated Serum Alpha-Fetoprotein Level in Hepatocellular Carcinoma Patients.

Cancers (Basel) · 2023 · PMC9954058 · PMID 36831565

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a decreasing trendno p-value reported

Abstract A recent study from the US showed a decreasing trend in the elevated serum alpha-fetoprotein (AFP) level (i.e., ≥20 ng/mL) in hepatocellular carcinoma (HCC) patients at the time of diagnosis.

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an increasing trendno p-value reported

Between 2011 and 2020, the proportion of patients with NBNC-HCC increased (which would have led to a decreasing trend in AFP elevation), which was counterbalanced by the decreased proportion of patients with BCLC stages 0–A HCC (which would have led to an increasing trend in AFP elevation).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.