The R 2 value of 0.813 means that the model can clarify 81.3% of the variability, and the associated p -value of less than 0.001 indicates the model is highly significant ( Table 3 ).
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Optimization of Spray Drying Process Parameters for the Preparation of Inhalable Mannitol-Based Microparticles Using a Box-Behnken Experimental Design.
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