Optimisation of AAV-NDI1 Significantly Enhances Its Therapeutic Value for Correcting Retinal Mitochondrial Dysfunction.

Pharmaceutics · 2023 · PMC9960502 · PMID 36839646

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did not quite reach significanceno p-value reported

AAV-ophNdi1 transduced cells demonstrated higher ATP levels (96.21 ± 35.79 pmol/min) compared to both the untransduced control cells (54.68 ± 19.75 pmol/min) and AAV-NDI1 transduced cells (58.76 ± 26.92 pmol/min) but did not quite reach significance ( n = 0.0689 pmol/min, ANOVA; n = 6).

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