Past, Present and (Foreseeable) Future of Biological Anti-TNF Alpha Therapy.

J Clin Med · 2023 · PMC9963154 · PMID 36836166

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highly significantno p-value reported

A further and highly significant improvement in the pharmacology of mAbs was achieved with the production of humanized mAbs that were developed by transplanting murine hypervariable segments of the complementary-determining regions (CDRs) into a human Ab structure [ 10 , 11 , 12 ].

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