"Self-inactivating" rabies viruses are susceptible to loss of their intended attenuating modification.

Proc Natl Acad Sci U S A · 2023 · PMC9963760 · PMID 37053554

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hedged sentence

0.0718

closest p · 1.4× alpha

0.0718

boldest claim

The sentences

not quite statistically significantP = 0.071820149so close (0.05 < p ≤ 0.1)

For example, using the NPEST virus with TEVP provided, the average number of remaining “source cells” (defined in this case as cells that were labeled by the virus and expressed both G and TEVP) dropped from 29 at 7 d to 2 at 3 wk [although here again the comparison was not quite statistically significant ( P = 0.071820149) due to the high variance and low number ( 3 ) of mice per group].

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