In a previous nested case–control study including 423 pairs of CRC cases and controls from the EPIC cohort, there was a marginally significant positive association between a BMI-related metabolomic signature and CRC risk (OR per 1-SD = 1.16, 95% CI: 0.99–1.35) before the adjustment for anthropometric measures including BMI [ 14 ].
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A Metabolomic Signature of Obesity and Risk of Colorectal Cancer: Two Nested Case-Control Studies.
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