FUS Alters circRNA Metabolism in Human Motor Neurons Carrying the ALS-Linked P525L Mutation.

Int J Mol Sci · 2023 · PMC9968238 · PMID 36834591

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closest p

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very close to significanceno p-value reported

Notably, quantitative analysis showed that circDLC1 is significantly downregulated in FUS P525L MNs, while circSLC8A1 has a p -value very close to significance ( Figure 4 b); however, both circRNAs were upregulated during MN differentiation ( Figure 4 c).

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