In addition, levels of the iron storage proteins, FtL and FtH, exhibited a decreasing trend after ECs Fpn1 knockout, which was congruent with the ICP-MS data, since the ferritin proteins are regulated by cellular iron content.
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Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke.
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