CD4<sup>+</sup> T cells expressing CX3CR1, GPR56, with variable CD57 are associated with cardiometabolic diseases in persons with HIV.

On the other hand, CGC + CD8 + T cells were not correlated with age, BMI, or waist circumference, and had a modest correlation with fasting blood glucose in non-diabetic/pre-diabetic PWH (r=0.27, p=0.009), and a trend toward significance in diabetic PWH (r=0.33, p=0.05) ( Figures 8I-L ) CGC + CD8 + T cells were also correlated with hsCRP (ρ=0.30, p =0.005) ( Figure 8M ) but not IL-4, IL-10, or IL-6 ( Figures 8N-P ).

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