Long-term Temporal Stability of Peripheral Blood DNA Methylation Profiles in Patients With Inflammatory Bowel Disease.

Cell Mol Gastroenterol Hepatol · 2023 · PMC9972576 · PMID 36581079

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Our results corroborate with previous array data showing highly significant correlations between CpG loci on several HLA class II genes of neonates compared with toddlers (r = 0.83) and adults (r = 0.88) with type 1 diabetes. 67 Although further interrogation of these HSMPs indicates that multiple CpGs might be actual genetic variants, we also find multiple HSMPs that are not genetic variants.

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