Nematode gene annotation by machine-learning-assisted proteotranscriptomics enables proteome-wide evolutionary analysis.

Genome Res · 2023 · PMC9977148 · PMID 36653121

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highly significantP -value < 10 −75actually significant

The overlap between the missed BUSCO genes in these two species is highly significant (more than 250 ORFs, P -value < 10 −75 , hypergeometric test), arguing for a strong sequence divergence or loss of these genes in more distant nematode lineages.

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