Barely Significant
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Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation.

Front Physiol · 2023 · PMC9979219 · PMID 36875035

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may be significantno p-value reported
Nevertheless, these studies show that estrogen deficiency and PTHrP can work in conjunction to activate bone loss in lactation, but they also suggest that there may be significant contributions from other local or systemic factors to the full effects of lactation on the skeleton.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.