Protective Effects of Crocin Against Methotrexate-Induced Hepatotoxicity in Adult Male Albino Rats: Histological, Immunohistochemical, and Biochemical Study.

As depicted in Table 1 , rats treated with a single injection of MTX demonstrated a highly significant increase (p < 0.001) in the serum levels of AST, ALT, and ALP enzymes in comparison to control and crocin-treated groups.

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