Barely Significant
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Contribution of alcohol use to the global burden of cirrhosis and liver cancer from 1990 to 2019 and projections to 2044.

Hepatol Int · 2023 · PMC9985909 · PMID 36871271

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an increasing trendno p-value reported
Deaths and DALYs are mainly distributed in people aged 40+ years, but there is an increasing trend in people aged under 40 years.

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a decreasing trendno p-value reported
The ASDR and standardized DALY rates for liver cancer due to alcohol use showed a decreasing trend with AAPC of −0.47 (95% CI: −0.66, −0.28) and −0.82 (95% CI: −0.93, −0.70), respectively.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.