Insights into the pharmacodynamics and pharmacokinetics of meldonium after exposure to acute high altitude.

Front Pharmacol · 2023 · PMC9992410 · PMID 36909160

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an increasing trendno p-value reported

The study results showed that the metabolite 3-hydroxypropionic acid showed an increasing trend with concentration and time in the high concentration group (100–400 μg/mL), while no increasing trend was found with increasing content in the low concentration group (4–40 μg/mL), but an increasing trend was found after 4 h of incubation.

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