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Left atrial dysfunction can independently predict exercise capacity in patients with chronic heart failure who use beta-blockers.

BMC Cardiovasc Disord · 2023 · PMC9996944 · PMID 36894879

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a decreasing trendno p-value reported
In a healthy population, LA reservoir strain showed a decreasing trend with increasing age [ 35 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.